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Studies have shown that DHEA is useful in patients with systemic lupus erythematosus. An application of the evidence was discussed by the U.S. Food and Drug Administration in 2007 and is available online. This review also shows that cholesterol and other serum lipids decrease with the use of DHEA (mainly a decrease in HDL-C and triglycerides can be expected in women, p110).

Dehydroepiandrosterone sulfate (DHEAS) is the sulfated version of DHEA. This conversion is reversibly catalyzed by sulfotransferase (SULT2A1) primarily in the adrenals, the liver, and small intestine. In the blood, most DHEA is found as DHEAS with levels that are about 300 times higher than those of free DHEA. Orally-ingested DHEA is converted to its sulfate when passing through intestines and liver. Whereas DHEA levels naturally reach their peak in the early morning hours, DHEAS levels show no diurnal variation. From a practical point of view, measurement of DHEAS is preferable to DHEA, as levels are more stable.

People are living longer than ever before, but if you think you're lucky to be part of this trend, think again. Our longevity is coming to us at tremendous cost in the form of an ever-increasing incidence of cancer, heart disease, Alzheimer's disease, osteoporosis, and other chronic degenerative diseases commonly associated with ageing. This is bad news indeed, especially when you stop to consider that there is no built-in mechanism that causes our bodies to start falling apart at a given age. In fact, there is compelling evidence to suggest that our rather sad health picture is due largely to environmental factors. Worse yet, these factors can be linked to chronic health problems not just among the elderly, but younger people as well. You can, however, take steps to keep yourself out of this grim scenario. And for today your strongest weapon - modern preparations containing DHEA. A healthy and growing body of scientific evidence points to DHEA as the single most important factor in our health. To understand how this is possible, we need to take a closer look at DHEA.

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